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Set apart for the work by the prophets and teachers at Antioch Paul and Barnabas with John Mark go down to the harbor of Seleucia and sail to Cyprus — beginning the first missionary journey that will plant churches across southern Galatia and inaugurate the Gentile mission of the church.
Acts 13:1-5 narrates the launch of Paul's first missionary journey from the harbor of Seleucia: "Now there were in the church that was at Antioch certain prophets and teachers; as Barnabas, and Simeon that was called Niger, and Lucius of Cyrene, and Manaen, which had been brought up with Herod the tetrarch, and Saul. As they ministered to the Lord, and fasted, the Holy Ghost said, Separate me Barnabas and Saul for the work whereunto I have called them... So they, being sent forth by the Holy Ghost, departed unto Seleucia; and from thence they sailed to Cyprus. And when they were at Salamis, they preached the word of God in the synagogues of the Jews." Seleucia Pieria served as the Mediterranean port of Antioch.
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